Psychological Status and Balance among Pregnant Women: A Comparison between Natural Pregnancy and in Vitro Fertilization- Short Communication


Pregnancy, also known as gestation, is the period during which one or more offspring develop inside a woman. The stages of pregnancy are divided into 3 trimesters, each lasting 3 months, and are characterized by distinct changes in mother and foetus (1). In vitro fertilization (IVF) is a form of assisted reproductive technology (ART) where eggs and sperm are combined in a laboratory dish before being transferred to the uterus (2).

The transition to motherhood is a dynamic period in life, characterized by significant neurobiological and psychosocial changes. These changes can have a profound impact on the physical and mental well-being of women and their offspring. Depressive symptoms impact over 25% of women during the peripartum period, with anxiety and related disorders affecting 10–20% (3). There is evidence indicating that maternal depression and anxiety symptoms can significantly impact infant development. Risk for peripartum depression and anxiety may be linked to some of the physiological changes (Shifts in hormones, neurobiological changes) that women experience during this period (3). New mothers’ ability to respond sensitively to their infants may be influenced by interactions between psychosocial and physiological factors. Research in rodents and humans has found evidence of reductions in brain volume and increases in ventricular size during the peripartum period (3).

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